Crabby Mama's Fundraising page
Raising funds for a potential ALS drug
Thanks for stopping by my page. I want to let you know where that money will be going.
ALS TDI has a drug that they have tested and out of the drugs they have tested over the years, this one AT1501:
In preclinical testing, AT-1501 produced the most exciting outcomes we have seen in the over 300 drugs tested since the inception of ALS TDI. In the gold standard SOD1 mouse model: • AT-1501 extended life span significantly; beyond any other drug that has been advanced into human ALS clinical trial,
• AT-1501 delayed disease onset,
• AT-1501 improved body weight, signaling that muscle is healthier,
• AT-1501 improved the percentage of neuro-muscular junctions that remain intact, allowing muscle to remain functional.
ALS TDI needs about 7 million dollars to get this to clinical trial. That is a huge amount of money, I know. But what ever we can raise at our Corntoss will bring us that much closer to the 7M and it will be more that TDI has now.
This drug is a huge deal. It could really really make a difference in the course of ALS. It could change it completely. It could slow the disease down and help keep muscle healthier longer. The one thing
I always think about when I think about the possibility of this drug getting to trial and then hopefully to market, is how it could help with swallowing. Pat LOVED his Grande Mochas! When it got to the point that he couldn’t swallow anymore, that was one of the things he missed the most. Yes, we were able to put his Mocha in his feeding tube, and he got the coffee/sugar jolt that way. But he missed tasting it.
If this drug could help Pat swallow his mocha for a longer amount of time, that would have made him happy. Of course, he missed the really really big things like walking, using his arms, hands, and driving, but really it was the simple things of the day that made life livable for him…like sipping a mocha.
I hope you consider making a donation on Pat\\'s behalf and on behalf of our family. ALS is a horrible disease and no family should have to live with it in their lives, or live through the aftermath of ALS no longer being a part of your life.
xo Jenny, Brenna, and Sean